BDBM12345 CHEMBL178090::US8609708, 2::US8609708, 47::[5-(pyridin-3-yl)furan-2-yl]methanamine::nicotine 3-heteroaromatic analogue 2a

SMILES NCc1ccc(o1)-c1cccnc1

InChI Key InChIKey=LENAVORGWBTPJR-UHFFFAOYSA-N

Data  3 KI  12 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 12345   

TargetCytochrome P450 2B6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM12345(CHEMBL178090 | US8609708, 2 | US8609708, 47 | [5-(...)
Affinity DataIC50:  1.91E+5nMpH: 7.5Assay Description:To gain insight into the selectivity of the synthetic compounds for inhibition of other CYPs, we examined the major CYPs present in human liver. Prio...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCytochrome P450 2B6(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM12345(CHEMBL178090 | US8609708, 2 | US8609708, 47 | [5-(...)
Affinity DataIC50:  1.91E+5nMAssay Description:Inhibitory concentration value against human cytochrome P-450 2B6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed